Funded Projects
FRRB firmly believes that a fairer and more inclusive future is built through knowledge and innovation. As stated in the foreword to the document Personalized Medicine – Development Potential of Precision Medicine in the Lombardy Region, “We cannot hope for a fair and inclusive future if we do not understand that, to achieve it, we must increasingly focus on the knowledge society.”
FRRB’s mission is to support and promote research and innovation in the biomedical field at regional, national, and international levels. We do this by funding original and innovative research projects, with the goal of improving citizens’ quality of life and strengthening the Lombardy Healthcare System.
Investing in knowledge and research is the path toward a fairer and more sustainable tomorrow for all.
Since 2015, FRRB has funded biomedical research projects selected through competitive procedures, participating in regional and European calls as a funding body.
The calls issued by FRRB finance projects that help to better understand specific diseases, describe their natural history, identify risk factors and biological mechanisms, and assess the safety and effectiveness of healthcare interventions (drugs, medical devices, vaccines, surgical procedures, and therapies). In recent years, attention has increasingly shifted toward initiatives aimed at improving diagnosis and prevention—for example, through the development of diagnostic tests, biomarkers, or screening algorithms—promoting the rapid introduction of innovative treatments and the phasing out of obsolete or ineffective practices.
As shown in the graph below, the research areas covered by FRRB funding are diverse, in order to address all the needs and demands of the Lombardy region.
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PROGETTO PIXEL Profiling and functional analysis of the Immune environment of eXtramedullary leukemia rELapses |
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PROGETTO LIPIDMAC Exploiting lipid-laden macrophages to overcome resistance to cancer immunotherapy |
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Progetto BOOST Progetto FRRB 3438840 - Bottom-up and tOp-down neuromOdulation of motor plaSTicity in cerebral palsy |
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Progetto Linking Park Progetto FRRB 3433068 - Linking inflammation to progression of neurodegeneration in Parkinson's disease |
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Progetto IN SIGNO Progetto FRRB 3423223 - Identification of Novel molecules Supporting the Impact of ß-lactams against clinically-relevant Gram-Negative multidrug resistant Organisms |
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Progetto MATRIx Progetto FRRB 3440227 - Mesenchymal stromal cells for curing traumatic brain injury |
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Progetto AMPROject Progetto FRRB 3414083 - AntiMicrobial Peptides-enriched silk fibroin scaffolds: a new strategy to boost the efficacy of conventional antibiotics in antimicrobial Resistance Orthopedic infections |
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Progetto Drop by drop Progetto FRRB 3441133 - Deciphering the molecular signature in Kleefstra syndrome: proof of principle working model for chromatinopathies |
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Progetto AI-CORPS Progetto FRRB 3432721 - Trustworthy, integrated Artificial Intelligence tools for predicting high-risk CORonary PlaqueS |
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Progetto TechNoPAIN Progetto FRRB 3440110 - A new digital technology-based treatment for chronic pain combining neuromodulation, computer-assisted training and telemonitoring |
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Progetto THYMALL Progetto FRRB 3439334 - Epigenetic modifiers of the GTF2I axis in thymomas and acute lymphoblastic leukemias: a new repurposing paradigm across rare tumors |
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Progetto Remodel Progetto FRRB 3444218 - Multiomics pRofiling of patient spEcific Models to predict druggable targets in severe neuromuscular rare diseases |
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Progetto INDAGA Progetto FRRB 3438215 - In depth analysis of salivary gland cancers: from cell lines and genomic evaluation towards clinical trials in locally advanced and recurrent/metastatic disease |
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Progetto MAINSTREAM Progetto FRRB 3430931 - A Multimodal Approach for Clinical Diagnosis and Treatment of Primary Progressive Aphasia |
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Progetto NeoPeSino Progetto FRRB 3421802 - Neoadjuvant pembrolizumab plus chemotherapy in locally advanced sinonasal carcinoma |
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PROGETTO CORSAI Raman analysis of saliva from COPD patients as new biomarker: AI-based point-of-care for the disease monitoring and management |
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PROGETTO PERCARD Personalised Prognostics and Diagnostics for Improved Decision Support in Cardiovascular Diseases |
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PROGETTO IMAGENE Epigenomic and machine learning models to predict pancreatic cancer: development of a new algorithm to integrate clinical, omics, DNA methylation biomarkers and environmental data for early detection of pancreatic cancer in high-risk individuals. |
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PROGETTO SYMMETRY Subclonal heterogeneitY and MicroenvironMEntal engagement as predictors for Treatment Resistance in lYmphoma |
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Progetto BIPCOM Medical comorbidities in bipolar disorder: clinical validation of risk factors and biomarkers to improve prevention and treatment |
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Progetto DEEPEN-iRBD Prodromal DEtErminants for PhENoconversion of idiopathic RBD to alpha-synucleinopathies (PD, DLB and MSA) |
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Progetto ONAKI-ICI Towards a personalised clinical management of oncologic patients with acute kidney injury associated to immunecheckpoint inhibitors |
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Progetto MG-PerMed Personalising myasthenia gravis medicine: from “onefits- all” to patient-specific immunosuppression |
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Progetto Stracyfic Patient Stratification by Standardization of the Image based Sweat Test for Cystic Fibrosis for use in Clinical Routine |
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PROGETTO AUTISMI Progetto FRRB 2679742 - Role of the Gut Vascular Barrier and Microbiota in Autism Spectrum Disorders |
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PROGETTO APRECOT Progetto FRRB 2681424 - Assessment of Predictors of Response to Cognitive Training in Patients with First Episode Psychosis. |
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PROGETTO SC_HGSOC Progetto FRRB 2729068 - Identification of druggable targets using single cell characterisation of epigenetic dysregulation in high-grade serous ovarian cancer. |
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PROGETTO MICBIORADIO Progetto FRRB 2721017 - Discovering the MicroBiota potential for personalised Radiotherapy |
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PROGETTO DELIVER Progetto FRRB 3269225 - Towards systematic characterisation of gene functions in adult organs: development of a liver-based in vivo essentiality screen |
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PROGETTO SILENCE-LQTS SGK1 inhibition as a novel therapeutic approach in Long QT syndrome |
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PROGETTO SCN1A-UP! Therapeutic strategies for Dravet syndrome: upregulation of endogenous SCN1A and modulation of pathological remodeling |
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PROGETTO TREAT-SGS Development and preclinical testing in human cell models and transgenic mice of a novel treatment for Schinzel-Giedion Syndrome |
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PROGETTO VASCO Progetto FRRB 1739635 - Functional and structural cerebrovascular alterations in neurological disorders: the role of complement |
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PROGETTO MuST-AS Progetto FRRB 1734478 - Multiple sclerosis: translating alternative splicing events into therapeutic targets and biomarkers. |
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PROGETTO GenTooControl Progetto FRRB 1751658 - Leveraging gene-based tools to control local and systemic circuits of tumor tolerance. |
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PROGETTO PANTHER Progetto FRRB 1740526 - Precision Medicine Applied to Leigh Syndrome at different stages: development of a Neonatal metabolic supplementation and a fetal gene THERapy approach. |
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PROGETTO UNEARTH Progetto FRRB 1745126 - A thorough understanding of the molecular players causing rare complement-mediated glomerular diseases toward a personalized therapy. |
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PROGETTO MODEL-MS-AGING Progetto FRRB 1750327 - Personalized brain organoid model of premature aging in multiple sclerosis. |
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PROGETTO ClulnhForPD Progetto FRRB 1737591 - Exploring LRRK2-Clusterin pathway as a therapeutic strategy for Parkinson’s disease. |
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PROGETTO GWAS-ATTR Progetto FRRB 1751723 - Genetic modifiers of hereditary and acquired ATTR amyloidosis. |
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PROGETTO PEPTIDE Progetto FRRB 1737173 - PLA2R-autoreactivE B-cell subsets in membranous nePhropaThy: Identification of outcome predictors and novel insights into Disease pathogenesis |
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PROGETTO CONNECTION Progetto FRRB 1731651 - Chnndroitin sulfate proteoglycan-4, secreted by a binding imbalance between SP1 and NF-kB on CHST11 gene, triggers sympathetic cardiac denervation in Duchenne Muscular Dystrophy. |
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PROGETTO NeOsReDy Progetto FRRB 1751150 - Restoring neural oscillatory communication between dorsal and ventral visual streams in developmental dyslexia |
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PROGETTO #METOOLIPO Progetto FRRB 1751036 - Precision medicine tools to advance management of liposarcoma patients. |
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PROGETTO VITA for NAFLD Progetto FRRB 1749055 - A very innovative therapeutic approach for non-alcoholic fatty liver disease and its complications |
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PROGETTO InflammaPark Progetto FRRB 1750818 - Decoding the molecular basis of the interplay between neuroinflammation and neurodegeneration in Parkinson’s disease. |
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PROGETTO CTC Mining ProgettoFRRB 1731093 - Interrogating circulating lung tumor cells to guide personalized therapies and identify novel targets to hit metastasis initiating cells. |
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PROGETTO PRESENT Progetto FRRB 1749118 - Exposures to PRenatal and postnatal adverse stressful Experiences: Multimodal omics signatures underlying Stress vulnerability and resilience and as Novel Targets for preventive strategies. |
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PROGETTO AIVAR Progetto FRRB ID 4981942 - Artificial Intelligence-Enhanced Diagnosis of PBC-AIH Variant Syndrome (AIVAR) |
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PROGETTO CANLAB Progetto FRRB ID 4986890 - Conformational Antibodies and Neuromuscular disorders and: LABoratory diagnostic and novel targets (CANLAB) |
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PROGETTO cHSPC-GT Progetto FRRB ID 4977394- Circulating hematopoietic stem cells as innovative target for gene therapy (cHSPC-GT) |
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PROGETTO CILIA Progetto FRRB ID 4976687- Cholangioids to dissect the genetic drivers of atypical Primary Sclerosing Cholangitis (CILIA) |
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PROGETTO EPIC-BAP Progetto FRRB ID Unlocking Precision Therapies: Epigenetic Control in BAP1-Mutated Tumors (EPIC-BAP) |
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PROGETTO FORECAST Progetto FRRB ID 4980460 - FluidOdynamics and plaque moRphology integrated assEssment to prediCt coronAry inStabiliTy (FORECAST) |
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PROGETTO FUN AT PLAQUE Progetto FRRB ID 4962566-Ficolin-2-dependent mechanisms of morpho-functional evolution of unstable atherosclerotic plaques (FUN AT PLAQUE) |
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PROGETTO GEAM Progetto FRRB ID 4977360 - Yield of GEnetic testing in Arrhythmic Myocarditis (GEAM) |
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PROGETTO GENETICA Progetto FRRB 4980634 - Evaluation of genetic-molecular causes of Out-ofHospital Cardiac Arrest: from patients to families (GENETICA) |
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PROGETTO LRRKINGTAUOPATHY Progetto FRRB ID 4969084- Dissect the interplay between LRRK2 and tau: implications for Alzheimer's disease (LRRKingTauopathy) |
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PROGETTO LONELYALS Progetto FRRB ID 4990089 - LONgitudinal and integrated Evaluation of biomarkers in reLation to phenotYpe in ALS (LONELYALS) |
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PROGETTO MINERVA Progetto FRRB ID 4984182 - Novel Method for diagnosis of neurodegenerative diseases based on saliva biochemical profiling (MINERVA) |
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PROGETTO MITOGEN-GBA Progetto FRRB ID 4986772- Effect of sex and GBA interaction on oxidative stress in shaping pd pathology: a multimodal study (MITOGEN-GBA) |
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PROGETTO MULTIFSGS Progetto FRRB ID 4972567 Multitarget therapy for primary podocytopathies with focal segmental glomerulosclerosis (MULTIFSGS) |
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PROGETTO MULTITREATALS Progetto FRRB ID 4959813-A multisystem and multitarget therapeutic approach to hamper Amyotrophic Lateral Sclerosis (MULTITREATALS) |
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PROGETTO OMNISAFE Progetto FRRB ID 4987503 - OMics-based newborn integrated screening for accurate false-positive easing: discovery of new signatures with an artificial intelligence approach (OMNISAFE) |
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PROGETTO RE-WALK-EASY Progetto FRRB 4969414 - Regaining walking ability easier and better in critical illness polyneuropathy and myopathy (RE WALK EASY) |
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PROGETTO SACS Progetto FRRB 4969522 - Role of SGLT-2 in the systemic manifestations of ANCA-associated vasculitis (SACS) |
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PROGETTO SPRINT-PD Progetto FRRB ID 4981375 - Somatic recombination and inflammatory signatures for Parkinson's disease diagnosis and treatment (SPRINT-PD) |
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PROGETTO SMA-TCHING Progetto FRRB ID 4956734 - Spinal muscular atrophy translating customized health innovations to newborn and grown-up patients (SMA-TCHING) |
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PROGETTO TARGET-TFR2 Progetto FRRB ID 4976651 -Identification of new strategies for in vivo targeting of erythroid Tfr2 in ß-thalassemia (TARGET-TFR2) |
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PROGETTO THE FAMILY STUDY Progetto FRRB ID 4957922- High-risk coronary atherosclerosis in subjects with family history of myocardial infarction (THE FAMILY STUDY) |
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PROGETTO DECODE Defining stratification of patients with C3 Glomerulopathies/immune complex-mediated glomerular diseases for better diagnosis and tailored treatment. |
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PROGETTO HIRISK-HIGAIN Rethinking personalized cancer therapy: targeting minimal residual disease in high-risk lymphoma patients |
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PROGETTO PERPLANRT Personalized Planning in Radio Therapy Through Integrative Modeling of Local Dose Effect and New Dosimetric Constraints |
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PROGETTO PRESERVE AI for new signatures and models for tailored organ preservation approaches in laryngeal and hypopharyngeal cancer. |
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PROGETTO EV-GLIO Plasma extracellular vesicles (EVs): the key for precision medicine in Glioblastoma |
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PROGETTO SuPerTreat Supporting Personalized Treatment Decisions in Head and Neck Cancer through Big Data. |
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PROGETTO PerBrain A Multimodal Approach to Personalized Tracking of Evolving State-Of-Consciousness in Brain- Injured Patients. |
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PROGETTO Serpentine Quantifying systemic immunosuppression to personalize cancer therapy. |
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PROGETTO PROGERIA The rarest of the rare – exploring non-coding RNA in the disease pathogenesis of Hutchinson-Gilford progeria syndrome. |
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PROGETTO DevDBA Ontogeny as a critical determinant of DBA sensitivity in red blood cell. |
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PROGETTO LQTS-NEXT LQTS-NEXT: to the NEXT level of risk prediction in patients with Long QTS Syndrome |
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PROGETTO INTESTRAT-CAD A prospective clinical study integrating multiomics and advance coronary imaging for risk stratification in coronary atherosclerosis. |
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PROGETTO CARE4NEURORARE An integrated omics approach for patients with rare neurological disorders: towards personalized clinical care and trial readiness. |
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PROGETTO IANG-CRC A regional oncology network addressing the emerging problem of colorectal cancer in young individuals using an integrative omics approach to decipher mechanisms of cancer immunoediting as candidate targets of new therapies. |
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PROGETTO NEVERMIND New frontiers of engineered nanovectors to improve treatment efficacy and safety in neurological disorders. |
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PROGETTO PLAGENCELL A network for cell and gene therapies for devastating diseases. |
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PROGETTO PRIMATE An integrated precision medicine approach to malignant mesothelioma: from mutation load to epidemiology and therapy |
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PROGETTO RADPrecise Personalized radiotherapy: incorporating cellular response to irradiation in personalized treatment planning to minimize radiation toxicity |
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PROGETTO LVADStrat Stratification of heart failure patients for cardiac recovery upon cardiac unloading by left ventricular assist device therapy: addressing the molecular, epigenetic, and proteomic changes associated with reverse cardiac remodelling. |
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PROGETTO FindingMS An integrated approach to predict disease activity in the early phases of Multiple Sclerosis |
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PROGETTO BATMAN Biomolecular Analyses for Tailored Medicine in Acne iNversa |
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PROGETTO QUANT-ALL Automated, absolute quantification of MRD in ALL patients by droplet microfluidics, single DNA copy barcoding and IG/TR amplicon NGS |
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PROGETTO TRANSCALL-2 Integration of genetic biomarkers and early Minimal Residual Disease to improve risk stratification and cure in childhood Acute Lymphoblastic Leukemia |
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PROGETTO SCRATCH Microbiota-based screening of anal cancer in HIV-infected individuals |
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PROGETTO IMMUNOCELL Single-cell immunophenotypic and transcriptomic profiling for minimally-invasive detection of early multiple myeloma |
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PROGETTO TRANS-ALS FRRB 2015-023 - Translating molecular mechanisms into ALS risk and patient’s well-being (TRANS-ALS) |
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PROGETTO REL FRRB 2015-042 - Genomic profiling of rare hematologic malignancies, development of personalized medicine strategies, and their implementation into the Rete Ematologica Lombarda (REL) clinical network |
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PROGETTO CMV FRRB 2015-043 - Pathogenesis and prevention of non primary human cytomegalovirus infection |
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PROGETTO LYRA FRRB 2015-010 - Single-cell analyses of lymphocytes that infiltrate autoimmunity sites: dissecting immunological mechanisms of rheumatoid arthritis |
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PROGETTO Acoma Optimization of Antibiotic Combinations using Organoids for treatment of Mycobacterium abscessus infections |
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PROGETTO Donate LyophilizeD fecal micrObiome traNsfer for primAry closTridioides difficilE infection (DONATE study): a multicenter randomized controlled trial |
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PROGETTO Fight AMR Novel global One Health surveillance approach to fight AMR using Artificial Intelligence and big data mining |
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PROGETTO Fugaci Fungal genomics and Antagonistic Community Interactions |
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PROGETTO Eureka Bonding molecular genotyping and phenotyping to outcome measures in AL amyloidosis: A EUropean REgistry and sample sharing networK to promote the diagnosis and management of light chain Amyloidosis |
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PROGETTO Predyt Predictive biomarkers in dystonia: defining the paradigm of monogenic dystonia to implement the diagnosis and prognosis of undiagnosed forms |
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PROGETTO Precise Biomarkers and outcome PREdictors of paediatriC nephrotIc syndrome: a genetic, transcriptomic and SEcretome multiomics study |
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PROGETTO Hydra Charting the epigenetic trajectory of progression towards metastatic colorectal cancer |
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PROGETTO Dice Epigenomic ragulation of cancer immunity by dietary intervention |
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PROGETTO Lungoids Subtype-specific Lung Cancer Organoids based on artificial ECM for Precision Oncology: Closing the Gap Between Preclinical Models and Patient Care |
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PROGETTO Titan Novel Cancer Therapy: Inducing Double-strand DNA Breaks to Foster Tumor Cell Death, Antigenicity and Immunotherapy Response in New Personalized Models |
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PROGETTO Hi-ROC Targeting Hypoxia with heavy ions to gain control of RadiOresistance Cancers |
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PROGETTO Sei Mito Speed the Efficacy of Idebenone on MITOchondrial Leber Hereditary Optic Neuropathy (LHON) targeting NQO1 |
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PROGETTO 3D Leuko Tad Topologically Associating Domains (TADs) boundary disruption and 3D genome alterations as targets in acute leukemia therapies |
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PROGETTO iCC-STRAT Risk stratification and subtyping of intrahepatic cholangiocarcinoma for early detection of recurrence and response to immuno-therapy |
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PROGETTO TPlex-EAC T-Plex-Capture: Isolation of neoantigen-specific CD8+ T cell receptors for patient-specific immunotherapy in esophageal adenocarcinoma (EAC) |
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GLIDE Glioblastoma: Leveraging Metabolic Dependencies for Personalized Treatment |
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TACTIC-P Targeting Tissue-Resident T Cells for Personalized Immunotherapy and Recurrence Prevention in Patients with Node-Positive Prostate Cancer undergoing PSMA-guided Surgery |
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I-BREAKFAST-2 Comprehensive Immunometabolic profiling of TNBC patients receiving chemoimmunotherapy plus/minus calorie restriction in the BREAKFAST2 trial |
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BRAVE Next-Generation Anti-Biofilm Strategies:Bacterial Extracellular Vesicles as Diagnostic and Therapeutic Tools to Overcome Antibiotic Resistance in Prosthetic Infections |
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CART-SEN Longitudinal tracking of CAR-T cell clonotypes and evaluation of CAR-T cell senescence in patients affected by B-cell malignancies |
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PAVE Personalized Aortic Valve Engineering to tackle fibro-calcific progression |
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BINGO MicroBiome-Driven Immunosuppression: Unlocking New Strategies for TNBC Treatment |
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NEO-DARK Unmasking Dark Neoantigens in Early-Onset Colorectal Cancer as a Novel Frontier for Cancer Immunotherapy |
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REACT Developing a Region-Wide Machine-Learning–Empowered Platform for Actionable Genomic Epidemiology of Antimicrobial-Resistant Bacterial Clones |
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EPIMAI Early and Precise Identification of brain MRI abnormalities in pediatric epilepsy through Artificial Intelligence |
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PANORAMA From PAtients to Neuromuscular Organoids in Refractory AChR+ Myasthenia grAvis: end-plate dysfunction, biomarker discovery and regeneration strategies |
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DIOGENE Development of multiple bioprinted Inflammatory eye models to study dry eye and Ocular Graft vs host disease (oGVHD) integrating tissue ENgineering for Enhanced research and therapies |
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SarcUS-PIBD Ultrasound Assessment of Sarcopenia in Pediatric Inflammatory Bowel Disease: A Prospective Validation Study |
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REBORN Regeneration of Esophageal tissue with BiOengineeRed Neovascularized scaffold |
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VISTE Vascular Insights into Sarcoma Treatment with Eribulin "VISTE" study, a Comprehensive Spatial and Functional Analysis of Eribulin-Induced Vasculature Remodeling in Sarcoma |
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RADARR Unraveling the Role of RAD51 in PARPi Resistance: From Molecular Insights to Therapeutic Strategies for Advanced Ovarian Carcinoma |
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IDEA PROJECT Investigating determinants of immunotherapy efficacy in endometrial cancer: a multidimensional approach in a unique population |
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IL-1R8CHEMOBEAT Characterization of IL-1R8 as a Novel Immune Checkpoint to Boost Chemotherapy and Mitigate Cardiotoxicity |
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Ribosomal pathologies: mechanistic therapy of Shwachman-Diamond syndrome |
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Synaptic dysfunction in Angelman syndrome: spatio-temporal trajectories and molecular mechanisms |
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Therapeutic approaches in spinal bulbar muscular atrophy (SBMA): exploiting the alternative AR-A isoform to mitigate the toxicity of the mutant androgen receptor that drives the disease |
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Addressing the metabolic and functional defects in neurons and oligodendrocytes in nasu hakola disease |
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Decoding disease diversity: the impact of missense mutations on FLVCR1 isoforms and their interaction networks. |
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Evaluating the Safety and Efficacy of ASO-Based Therapy in the Murine Model of Schinzel-Giedion Syndrome |
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AAV9-mediated gene replacement strategy for the treatment of Charcot-Marie-Tooth type 4B1 and B2 neuropathies with aberrant myelin |
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AAV gene therapy for Marinesco-Sjögren syndrome: optimizing delivery, expression and therapeutic timing for clinical translation |
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CC4C Closer Care for Children: Transitioning from institutionalized to home and community-based delivery models for pediatric rehabilitation |
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P.R.I.M.E. Primary Care and Mental Health Ecosystems: Towards Sustainable and Community-Based Care Pathways |
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WISH Early breast cancer, follow-up, hormonal treatment, drug toxicity, lifestyle intervention, remote patient monitoring, community health service |
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MT2-ASD Melatonin MT2-Selective Agonists as a Novel Treatment for Fragile X Syndrome (FXS) and Phelan-McDermid Syndrome (PMS) |
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SynLeigh Towards synergistic treatments for Leigh Syndrome Spectrum disorders |
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T-CARE T-cell-based Approaches for Controlling Autoimmune disease with Epilepsy |
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BIOKID-PG Genomics, metabolomics, transcriptomics, inflammatory bowel disease, pediatrics, anti-TNF drugs, pharmacogenomics |
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IMPACT-CRC CRC, immunotherapy, multi-omics, bioinformatics/AIML, biomarkers, methodology |
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Optimize Multiomics signature to customize induction or neoadjuvant treatments for optimizing laryngeal preservation strategies. |
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PRECISION-tMN Therapy-related myeloid neoplasms (t-MN), Hypomethylating Agents (HMA), Precision medicine, Epigenetics, Multi-omics integration, Patient-derived in vitro testing, in silico modeling. |
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TRANS-AML-EU Transforming Personalised Acute Myeloid Leukaemia Therapy through an Integrative European Multi-Centre Multi-Omics Network |
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MIND Multi-omics prediction modelling of brain metastasis management in breast cancer |
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Glio-SCREEN Advancing Glioblastoma Treatment: the combination of Omics, Drug Screening, Liquid Biopsy, and artificial intelligence for precision oncology |
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OPTIMAL Optimizing precision T-cell redirecting therapies in refractory/relapsed large-B cell lymphoma |
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ECLIPSE Epigenetic changes in long COVID patients: unravelling the gutimmune axis and therapeutic targets |
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EV-PREDICT Extracellular vesicle-based molecular signatures for personalizing neoadjuvant treatment in triple negative breast cancer |
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PREDICT Predictive response and disease evolution in ovarian cancer with generative AI |
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PRECURSOR-HCC Lipid droplet retention asthe causal driver of progressive steatotic liver disease - hepatocellular carcinoma |
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MEDAL Diagnosis, pathogenesis and innovative therapiesfor metabolic lysosomal storage diseases with skeletal involvement |
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AI-PARKNET A personalized model of care for Parkinson disease based on AIinformed multimodal stratification of patients |
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DTPDAC Deciphering and targeting the immunological niche in PDAC |
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IMPACT-ALL Innovative strategies for advanced molecular and metabolic targeting of pediatric and adult acute lymphoblastic leukemia to personalized treatments |
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