Dettaglio Progetto Finanziato

TACTIC-P

Despite curative-intent radical prostatectomy and PSMA-guided lymphadenectomy, high-risk, locally advanced prostate cancer often recurs also due to immune-evasive tumor features. Current immunotherapies show limited efficacy. Here we propose a personalized approach to activate pre-existing resident T cells in the prostate, reprogram the tumor microenvironment, and drive systemic anti-tumor immunity.