FRRB is pleased to announce the release of the new EP PERMED (European Partnership on Personalised Medicine) Joint Transnational Call (JTC 2026).  

Project proposals should address one or more of the following aspects: 

• Development and validation of innovative personalised therapeutic approaches for cardiovascular, metabolic or kidney diseases through testing in relevant pre-clinical models (e.g., human cell cultures, organoids, organs-on-chips, disease-specific animal models, or in silico models).  

• Identification and validation of molecular markers/signatures or cutting-edge technologies to monitor treatment response in patients with cardiovascular, metabolic or kidney diseases in order to tailor treatment pathways. This may include the analysis of the treatment effectiveness or treatment-related (including multi-medication) adverse effects as well as dose optimisation. 

• Identification and validation of stratifying molecular markers/signatures or stratifying diagnostic technologies for early disease risk prediction and prevention of disease worsening or comorbidities in patients with cardiovascular, metabolic or kidney diseases, thereby delaying the progression to cardiovascular-kidney-metabolic syndrome. 

Research projects are encouraged to include these aspects into the proposal: 

• Multi-omics data such as genomics, epigenomics, metagenomics, transcriptomics, proteomics and metabolomics data in relation to treatment outcomes. These data may be obtained from health data platforms or infrastructures, including population-level health databases. 

• Cutting-edge technologies such as AI/ML algorithms, next-generation imaging technologies, digital health tools, etc. to enhance early diagnosis, monitor treatment response, optimise therapy effectiveness or dosage, and detect or prevent comorbidities and treatment-related side effects in patients. 

• Information regarding patient medication, dose or compliance, medication efficacy, adverse effects, patient reported outcomes (PRO) or patient preferences. 

• Additional factors such as sex/gender dimension, age, environmental and social background, lifestyle, or nutritional status 

FRRB joins the Call as a funding agency: Regional Health Service bodies (ASSTs, public and private IRCCSs, AREUs and ATSs), universities and research centres based in Lombardy will have the opportunity to submit a project proposal and obtain funding for their activities from the Regional Foundation for Biomedical Research. 

For this Call FRRB has allocated a total budget of Euro 500.000,00.    

More information on the official project page: EP PerMed Joint Transnational Call (JTC) 2026 – European Partnership for Personalised Medicine – EP PerMed 

An information day will be held on 16^th December 2025. Information on how to register and participate is on the official https://www.eppermed.eu/news-events/events/ep-permed-jtc2026-information-day/ 

Pre-eligibility  

In order to obtain funding from FRRB, Lombardy-based entities must complete a pre-eligibility form, which can be downloaded from this page, in the “documents to download” section.

Pre-eligibility forms must be submitted via the new FRRB Call for Proposals Platform (https://bandi.frrb.it/login), available from December 9, 2025.

FRRB also provides candidates with a template for drawing up their budget (“Budget tool”). The budget tool is intended as a support tool for internal use by candidates and is not an official document of the 2026 call.